Cinnamon, a common kitchen staple known for its sweet, warm flavor, is widely used in everything from baked goods to beverages. However, recent research by scientists at the University of Mississippi suggests that while cinnamon may enhance flavor, it can also interfere with the effectiveness of certain prescription medications, especially when consumed in large quantities.

Cinnamaldehyde and Its Impact on Medications

The key compound in cinnamon that raises concern is cinnamaldehyde. According to the study, cinnamaldehyde has the ability to activate specific receptors in the body that can speed up the breakdown of certain medications. This rapid clearance can significantly reduce the efficacy of the drugs, making them less effective in managing the conditions they are meant to treat.

Dr. Shabana Khan, a principal scientist involved in the study, emphasized that moderate use of cinnamon — such as a sprinkle in your coffee or on toast — is generally not harmful. However, she warned that excessive intake, especially in the form of supplements, may cause serious complications if taken without medical supervision.

Supplements and Overconsumption: A Dangerous Mix

The study draws particular attention to cinnamon supplements, which are often marketed as natural health boosters. People may unknowingly take these in high doses, assuming they are harmless due to their natural origin. Dr. Khan highlighted the risk this poses, particularly for individuals who are on prescription medications.

“Health concerns could arise if excessive amounts of supplements are consumed without the knowledge of a healthcare provider or the prescriber of the medications,” Khan explained. The problem, she noted, is that supplements could alter the body’s metabolism, leading to medications being flushed out too quickly, potentially making them ineffective or even dangerous.

Cassia vs. Ceylon Cinnamon: Why the Type Matters

Not all cinnamon is created equal. The study makes a clear distinction between two primary types of cinnamon: Cassia and Ceylon. Cassia cinnamon, which originates in China and is commonly found in grocery stores due to its lower cost, contains higher levels of coumarin, a natural compound with anticoagulant properties.

Amar Chittiboyina, co-author of the study and associate director at the National Center for Natural Products Research, explained that coumarin can pose health risks, particularly for people taking blood-thinning medications. In contrast, Ceylon cinnamon — often labeled as “true cinnamon” and sourced from Sri Lanka — contains significantly less coumarin, making it a safer alternative in terms of medicinal interactions.

Cinnamon Oil Is Safe, But Bark Requires Caution

Interestingly, the study noted that cinnamon oil, which is often used in cooking, aromatherapy, and personal care products, does not appear to pose the same risks as cinnamon bark. It’s the bark, particularly that of Cassia cinnamon, that raises red flags. The oil’s processing and usage differ in a way that limits its interaction with medication metabolism pathways.

Advice for Those with Chronic Conditions

The researchers strongly advise individuals with chronic health conditions — including diabetes, hypertension, cancer, arthritis, asthma, HIV/AIDS, obesity, or depression — to consult with a healthcare provider before using cinnamon supplements. Even though these supplements are easily accessible and marketed for wellness, they are not regulated in the same way as pharmaceutical drugs and may carry unintended side effects.

“Our best advice is to talk to a health care provider before using any supplements along with prescription medicine,” Khan reiterated. “By definition, supplements are not meant to treat, cure, or mitigate any disease.”